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It’s an excellent solution in severe cases of hypogonadism that present with acute symptoms requiring immediate intervention.9 However, its side effect profile can be a significant barrier for many men, as its attendant spikes and drops in testosterone between injections can result in mood swings and other unpleasant symptoms.8 It’s also been shown to render men who regularly use it mostly infertile, making it a poor choice for men hoping to have children in the near future.2 Topical testosterone cream Topical testosterone cream is an excellent alternative to injectable testosterone cypionate for men who’d rather avoid needles
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